Mayo Clinic Published Clinical Trial
Our clinical trial, conducted at Mayo Clinic and published in peer-reviewed medical literature, demonstrated statistically significant reductions in LDL and total cholesterol — in just 30 days.
A cardiologist's plain English breakdown of what causes high cholesterol, the various treatments available, and the foods and supplements that can help.
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Clinically proven to help lower LDL cholesterol in 30 days. No prescription required.
As evaluated at Mayo Clinic and University of Manitoba.

Per serving
Unlike brands that rely on buzzwords and pseudoscience, Step One Foods is backed by a randomized, controlled clinical trial published in collaboration with Mayo Clinic. These are not funky powders. It is real food that really works.
Our clinical trial, conducted at Mayo Clinic and published in peer-reviewed medical literature, demonstrated statistically significant reductions in LDL and total cholesterol — in just 30 days.
Dr. Elizabeth Klodas spent 20+ years as a preventive cardiologist trained at Mayo Clinic and Johns Hopkins—prescribing medications, managing risk factors, hitting the numbers. Thousands of patients later, the pattern was undeniable: more drugs, more side effects, no cures. Her epiphany?
She wasn’t fixing what was making people sick.
The system rewards yet another prescription. Meanwhile, patients are surrounded by foods that quietly but relentlessly drive the very diseases that require all those drugs in the first place.
She envisioned a different approach—make food part of the solution.
And in conjunction with Mayo Clinic and the University of Manitoba she proved, decisively, that small dietary adjustments using targeted, precisely formulated foods can yield medication-level cholesterol reductions — in as little as 30 days.
Real outcomes from a peer-reviewed, free-living clinical trial of Step One Foods.
For those already on statins, adding Step One can provide that extra push to finally reach your target goal — without increasing your medication dosage.
No mystery. Here's the realistic timeline — what changes in your body, and when.
Two servings a day. Most people swap a typical breakfast and snack — no recipes, no calorie counting.
Steadier energy, less mid-morning hunger, and noticeably better digestion as fiber and omega-3 intake climb.
Recheck your LDL. In the Mayo Clinic trial, 80% of participants lowered LDL — by an average of 8.8% in 30 days.
Step One Foods was designed specifically for three groups that medications have failed.
Muscle pain, liver concerns, and other side effects make statins impossible for many patients — even those who need cholesterol support most.
Young or otherwise healthy individuals with abnormal cholesterol levels who prefer to try a food-first approach before committing to a lifetime of medications.
For patients already on the highest tolerated statin dose but still not at LDL goal, Step One Foods can provide meaningful additional reduction.
We never advocate that anyone stop or reduce their medications without first consulting their physician.
Rapid cholesterol lowering is merely the proof point. These foods deliver comprehensive cardiometabolic support — because food doesn't have side effects, just side benefits.
Clinically proven LDL reduction — the proof point of food's power.
Omega-3s and whole food fiber support healthy blood pressure levels.
Fiber-rich, low glycemic foods help improve glucose control.
Antioxidants from real whole foods combat chronic inflammation.
Nutrient-dense, satisfying foods that replace less healthy choices.
Essential prebiotic fiber nourishes beneficial gut bacteria.
These aren't testimonials about feeling better. These are real blood test results.
Dropped 44 mg/dL in 30 days
“My doctor was shocked. I told her I just changed my breakfast. She asked me what I was eating — now she recommends Step One to her other patients.”
Dropped 38 mg/dL in 30 days
“I was about to start statins. My cardiologist suggested trying this first. 30 days later, my LDL dropped 38 points. No statins needed.”
Dropped 42 mg/dL in 30 days
“I've tried everything — diet changes, exercise, supplements. Nothing moved the needle like this. The bars actually taste good too, which helps.”
*Individual results may vary. These are real customers sharing their actual blood test results.
Yes, and that rests on real evidence, not marketing. Step One Foods was developed by a preventive cardiologist and tested in a randomized controlled trial conducted with Mayo Clinic and the University of Manitoba, held to the same standard as a pharmaceutical trial. In that study, 80% of participants lowered their LDL cholesterol within 30 days while eating two servings a day. Every serving delivers precise, clinically meaningful amounts of the nutrients shown to lower cholesterol and support cardiovascular health.
Most "heart healthy" labels are marketing claims, not clinical results. Step One is different on two counts. First, it is designed like a combination therapy: whole-food fiber, plant sterols, omega-3 fatty acids, and antioxidants that lower cholesterol through several pathways at once, in the amounts used in our trial. Second, that trial actually happened — Step One Foods is backed by a published, peer-reviewed clinical trial demonstrating statistically significant LDL reduction. Claims are easy. Proof is rare.
Yes — in fact, they work well together. Statins lower cholesterol by blocking its production in the liver, while Step One Foods works largely on the absorption side, so combining the two produces an additive effect and can help you reach your goal faster. Never stop a prescribed statin on your own, though. The best approach is to keep taking it, add two servings a day, retest your cholesterol after about 30 days, and let your provider help you decide whether anything should change from there.
First, know that you've still done something meaningful: adding 10 grams of fiber a day — the amount in two servings of Step One — is associated with a 14% lower risk of heart events and a 27% lower risk of dying from heart disease. But if you don't see the cholesterol response you were hoping for, we'll refund what you paid for the products, up to one month's worth. That's how confident we are in the science.
60 servings. 30 days. Measurable results — or your money back. HSA/FSA eligible.
